GDC-0349

• Catalog number
  B1729-5
• Price
  Please ask
• Size
  5 mg

• Alternative_name
  GDC-0349; GDC0349; GDC 0349; RG7603; 1-ethyl-3-[4-[4-[(3S)-3-methylmorpholin-4-yl]-7-(oxetan-3-yl)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-2-yl]phenyl]urea; (S)-1-ethyl-3-(4-(4-(3-methylmorpholino)-7-(oxetan-3-yl)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-2-yl)phenyl)urea
• Description
  GDC-0349 is a potent and selective ATP-competitive inhibitor of mTOR with Ki value of 3.8 nM.
• CAS Number
  1207360-89-1
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₂₄H₃₂N₆O₃
• Molecular Weight
  452.55
• Cell Permeable
  Yes
• Purity
  >98%
• Solubilities
  DMSO
• Handling
  Protect from air and light
• Tag Line
  A potent and selective ATP-competitive inhibitor
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• MDL Number
  MFCD22417087
• PubChem CID
  59239165
• PubChem CID Link
• SMILES
  CCNC(=O)NC1=CC=C(C=C1)C2=NC3=C(CCN(C3)C4COC4)C(=N2)N5CCOCC5C
• InChi
  InChI=1S/C24H32N6O3/c1-3-25-24(31)26-18-6-4-17(5-7-18)22-27-21-12-29(19-14-33-15-19)9-8-20(21)23(28-22)30-10-11-32-13-16(30)2/h4-7,16,19H,3,8-15H2,1-2H3,(H2,25,26,31)/t16-/m0/s1
• InChi Key
  RGJOJUGRHPQXGF-INIZCTEOSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  GDC-0349  
• Short name
  GDC-0349
• Alternative name
  GDC-0349

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