GDC-0941

• Catalog number
  1623-5
• Price
  Please ask
• Size
  5 mg

• Alternative_name
  2-(1H-Indazol-4-yl)-6-[[4-(methylsulfonyl)-1-piperazinyl]methyl]-4-(4-morpholinyl)-thieno[3,2- d]pyrimidine
• Description
  GDC-0941 is a potent inhibitor of p110α and p110δ (IC₅₀ = 3 nM). It selectively binds to PI3K isoforms in an ATP-competitive manner, inhibiting the production of the secondary messenger phosphatidylinositol-3,4,5-trisphosphate (PIP3) and activation of the PI3K/Akt signaling pathway.
• CAS Number
  957054-30-7
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₂₃H₂₇N₇O₃S₂
• Molecular Weight
  513.64
• Cell Permeable
  Yes
• Purity
  ≥99% by HPLC
• Solubilities
  DMSO
• Handling
  Protect from air and light
• Tag Line
  A PI3 Kinase inhibitor
• Storage Condition
  -20°C
• Shipping Condition
  RT
• Shelf Life
  24months
• MDL Number
  MFCD11616196
• PubChem CID
  17755052
• PubChem CID Link
• SMILES
  CS(=O)(=O)N1CCN(CC1)CC2=CC3=C(S2)C(=NC(=N3)C4=C5C=NNC5=CC=C4)N6CCOCC6
• InChi
  InChI=1S/C23H27N7O3S2/c1-35(31, 32)30-7-5-28(6-8-30)15-16-13-20-21(34-16)23(29-9-11-33-12-10-29)26-22 (25-20)17-3-2-4-19-18(17)14-24-27-19/h2-4,13-14H,5-12,15H2,1H3,(H,24,27)
• InChi Key
  LHNIIDJUOCFXAP-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  GDC-0941  
• Short name
  GDC-0941
• Alternative name
  GDC-0941

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