BML-284

• Catalog number
  B1077-10
• Price
  Please ask
• Size
  10 mg

• Alternative_name
  2-Amino-4-[3,4-(methylenedioxy)benzylamino]-6-(3-methoxyphenyl)pyrimidine
• Description
  BML-284 is cell-permeable Wnt signaling pathway agonist. It mimics the effects of a Wnt ligand in a Xenopus model and may be a useful tool in the study of physiological processes that involve the Wnt signaling pathway due to activation of Wnt without inhibiting the activity of GSK-3β; it induces in vitro β-catenin and transcription factor (TCF) dependent transcriptional activity in 293T cells in a dose-dependent manner with an EC₅₀ of 700 nM.
• CAS Number
  853220-52-7
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₁₉H₁₈N₄O₃
• Molecular Weight
  350.37
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO (>25 mg/ml)
• Handling
  Protect from air and light
• Tag Line
  A potent and selective activator of Wnt signaling
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• PubChem CID
  11210285
• PubChem CID Link
• SMILES
  COC1=CC=CC(=C1)C2=CC(=NC(=N2)N)NCC3=CC4=C(C=C3)OCO4
• InChi
  InChI=1S/C19H18N4O3/c1-24-14-4-2-3-13(8-14)15-9-18(23-19(20)22-15)21-10-12-5-6-16-17(7-12)26-11-25-16/h2-9H,10-11H2,1H3,(H3,20,21,22,23)
• InChi Key
  FABQUVYDAXWUQP-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  BML-284  
• Short name
  BML-284
• Alternative name
  BML-284

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