GW5074 ,c-Raf1 kinase inhibitor
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Catalog number
SIH-451-2X5MG
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Price
Please ask
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Size
2X5 mg
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Research Area s
Cell Signaling , Cancer , Apoptosis , Cancer Growth Inhibitors , Tyrosine Kinase Inhibitors
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Category
Small Molecules
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Product Type
Inhibitor
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CAS No
220904-83-6
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MolecularFormula
C15H8Br2INO2
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Molecular Weight
520.9
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Purity
≥98% (TLC)
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Solubility
Soluble to 1 mM in ethanol and to 100 mM in DMSO
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Appearance
Yellow to orange solid
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Storage Temperature
-20°C
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Shipping Temperature
Shipped Ambient
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Description
Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.
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Gene target
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Short name
GW5074 ,c-Raf1 kinase inhibitor
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Alternative name
GW5074 ,c-v-raf-1 murine leukemia viral oncogene homolog 1 phosphorylation catalyst suppressor
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Alternative to gene target
v-raf-1 murine leukemia viral oncogene homolog 1, c-Raf and CMD1NN and CRAF and NS5 and Raf-1, RAF1 and IDBG-19277 and ENSG00000132155 and 102724915,5894, transferase activity, nuclei, Raf1 and IDBG-179428 and ENSMUSG00000000441 and 110157, RAF1 and IDBG-646381 and ENSBTAG00000004514 and 521196
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