DiscoveryPak™ RAF Kinase Inhibitor Set

• Catalog number
  S240-9
• Price
  Please ask
• Size
  9 inhibitors

• Description
  A convenient set containing nine (9) RAF kinase inhibitors. The set contains 25 mg of BAY 43-9006 mesylate (Cat. No. 1594); 5 mg of Encorafenib (Cat. No. B2103); 5 mg of GSK-2118436 mesylate (Cat. No. 2800); 5 mg of GW-5074 (Cat. No. 2412); 5 mg of PLX-4032 (Cat. No. 2235); 5 mg of PLX-4720 (Cat. No. 2813); 5 mg of RAF265 (Cat. No. 2856); 5 mg of TAK-632 (Cat. No. 2473), and 1 mg of ZM-336372 (Cat. No. 1789).
• CAS Number
  See under the individual products
• Structure Available
  See under the individual products
• Salt Form
  No
• Molecular Formula
  See under the individual products
• Molecular Weight
  See under the individual products
• Cell Permeable
  Yes
• Purity
  See under the individual products
• Solubilities
  DMSO
• Handling
  Protect from air and light
• Tag Line
  A RAF Kinase inhibitors set
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• SMILES
  N/A
• InChi
  N/A
• InChi Key
  N/A
• Data Sheet Link
• MSDS Available
  Yes
• Additional description
  Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.

• Gene target
  DiscoveryPak™   RAF   Kinase   Inhibitor   Set  
• Gene symbol
  RAF1
• Short name
  DiscoveryPak™ RAF Kinase Inhibitor Set
• Alternative name
  DiscoveryPak™ RAF phosphorylation catalyst suppressor Set
• Tissue
  set

Gene info

• Identity
  HGNC:9829
• Gene
  RAF1
• Long gene name
  Raf-1 proto-oncogene, serine/threonine kinase
• Synonyms gene name
  • v-raf-1 murine leukemia viral oncogene homolog 1
• Synonyms
  • Raf-1
  • c-Raf
  • CRAF
• Synonyms name
  • C-Raf proto-oncogene, serine/threonine kinase
• GenBank acession
  • X03484
• Locus
  3p25.2
• Discovery year
  1986-01-01
• Entrez gene record
  5894
• Pubmed identfication
  • 1611909
• RefSeq identity
  • NM_002880
• Classification
  • Mitogen-activated protein kinase kinase kinases
  • RAF family
• VEGA ID
  OTTHUMG00000129789
• Locus Specific Databases
  • LRG_413

MeSH Data

• Name
  Micropore Filters
• Concept
  Scope note: A membrane or barrier with micrometer sized pores used for separation purification processes.
• Tree numbers
  • E05.196.454.403
  • E07.560
• Qualifiers
  parasitology, microbiology, ethics, virology, trends, veterinary, history, classification, economics, standards, supply & distribution, adverse effects, statistics & numerical data

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