STF-62247, Autophagy inducer

• Catalog number
  SIH-396-10MG
• Price
  Please ask
• Size
  10 mg

• Stock availabilitIn Stock
  In Stock
• CAS number
  315702-99-9
• Description
  Autophagy inducer
• Molecular weight
  267,35 g/mol
• Primary research fields
  Cancer, Autophagy
• Other name
  N-(3-Methylphenyl)-4-(4-pyridinyl)-2-thiazolamine
• Product category
  Small Molecules
• Product type
  Inducer
• Chemical formula
  C15H13N3S
• Origin
  Synthetic
• Purity pourcentage
  ≥98%
• Soluble in
  Soluble in DMSO (26 mg/ml).
• Physical appearance
  Solid
• Storage recommendations
  -20ºC
• Shipping recommendations
  Shipped Ambient
• Safety information
  Classification: D1B- Toxic Material Causing Immediate and Serious, Toxic Effects, Toxic by ingestion, D2B- Toxic Material Causing Other Toxic Effects, Moderate eye irritant Safety Phrases: S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. Hazard statements: H302- Harmful if swallowed. H319- Causes serious eye irritation. Precautionary statements: P305 + P351 + P338- IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
• PubChem number
  704473
• Scientific context
  STF-62247 is a selective cell-permeable inducer of autophagy. This is demonstrated by an induction of large vacuole formation in cells. This observation is especially pronounced in von Hippel-Lindau deficient renal carcinoma cells. Induction of autophagy is also seen in vivo in mice.
• Bibliography
  1. Turcotte S., et al. (2008) Autophagy, 4(7): b944-6.
• Release date
  31-Mar-2014
• PubMed number
  Refer to PubMed
• Tested applications
  To be tested
• Tested reactivity
  To be tested
• Representative figure link
• Representative figure legend
  Chemical structure of STF-62247 (SIH-396), a Autophagy inducer. CAS #: 315702-99-9. Molecular Formula: C15H13N3S . Molecular Weight: 267.35 g/mol. Chemical structure of STF-62247, a Autophagy inducer (SIH-396). CAS # 315702-99-9. Molecular Formula: C15H13N3S .
• Warning information
  Non-hazardous
• Country of production
  Canada
• Total weight kg
  0.25
• Net weight g
  0.01
• Other related products

• Gene target
  STF-62247   Autophagy   inducer  
• Gene symbol
  PDX1
• Short name
  STF-62247, Autophagy inducer
• Alternative name
  STF-62247, Autophagy inducer

Gene info

• Identity
  HGNC:6107
• Gene
  PDX1
• Long gene name
  pancreatic and duodenal homeobox 1
• Synonyms gene
  • IPF1
• Synonyms gene name
  • insulin promoter factor 1, homeodomain transcription factor
• Synonyms
  • IDX-1
  • STF-1
  • PDX-1
  • MODY4
• Synonyms name
  • somatostatin transcription factor 1
• GenBank acession
  • AF035260
• Locus
  13q12.2
• Discovery year
  1995-01-30
• Entrez gene record
  3651
• Pubmed identfication
  • 7590740
• RefSeq identity
  • NM_000209
• Classification
  • HOXL subclass homeoboxes
• VEGA ID
  OTTHUMG00000016638

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