-
Description
Human Oncology Multi-Gene Mutations Detection Kit (High-Through Sequencing) is used to detect and identify the mutation of 13 gene, the identification of specific gene mutation helps to determine if we can benefit from targeted drug treatment. This kit is a key for the patient to manage whole-process disease
-
-
Specifications
16tests/kit
-
Other Name
Detection Kit for Human Multi- Gene Mutation
-
Detection Process
DNA/RNA extraction (RNA reverse transcription) + library construction (3,5 Hours)+ Sequencing+ One click data analysis
-
Samples Types
Anticoagulant venous blood collection tube 10 ml Peripheral Blood, 7 section FFPE, 50-500 ml Pleuroperitofluids
-
Gene
EGFR, KRAS,NRAS,EML4-ALK, KIF5B-RET, ROS1 Fusion, Other PTKs' fusion, CTNNB1, MET, BRAF, PIK3CA, PDGFRA, HER-2
-
Reactivity
Human
-
Advantages and Characteristics
Easy operation: library construction can be done in two steps,Rapid Detection: Library construction takes only 3.5 hours, and it takes only 2 working days from sample extraction to report completing. High sensitivity With 20,000 ⨯sequencing depth, up to 0.1% sensitivity ,this kit achieves drug resistance monitoring of the liquid biopsy samples. Comprehensive Inspection: : As one targeted drug recommended by both the domestic and the foreign authorities, this kit can detect 13 mutant genes, 389 existing targeted drug-related COSMIC locus in one time, and it can make a comprehensive analysis of non-small cell lung cancer and colorectal cancer.
-
Use
CE-IVD
-
Additional description
The detections of the targets with this kit is a type of test that can be performed on any target containing biological samples after clean up of interfering agents. The assay must be performed following the protocol. cDNA genes are a locus (or region) of DNA for functional transcript RNA or protein. An ELISA is used to detect the expressed protein in biological fluids, serum, saliva.
-
Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
-
Test
Sequencing primers for deep sequencing kits give sequencing nucleic acid results of DNA libraries, cDNAs. The MiSeq, HiSeq and NextSeq sequencing primers are designed to sequence the whole transcriptome.
-
Gene target
-
Short name
Oncology Multi- Mutations Kit ( -Through Sequencing)
-
Technique
sequencing, detection, multi, multi, sequencings
-
Species
Human, Humans
-
Alternative name
Oncology Multi-Gene Mutations Detection Kit
-
Alternative technique
sequencings, kits
-
Alternative to gene target
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog, C-Kit and CD117 and PBT and SCFR, KIT and IDBG-18980 and ENSG00000157404 and 3815, transferase activity, Extracellular, Kit and IDBG-172083 and ENSMUSG00000005672 and 16590, KIT and IDBG-642326 and ENSBTAG00000002699 and 280832
-
Disease
lung adenocarcinoma, variety of cancer
-