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ILK Polyclonal Antibody

CAT: 0763-D-AB-10466L-01Size: 25 µLDry Ice: NoHazardous: No
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CAT#:0763-D-AB-10466L-01Size:25 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a protein with a kinase-like domain and four ankyrin-like repeats. The encoded protein associates at the cell membrane with the cytoplasmic domain of beta integrins, where it regulates integrin-mediated signal transduction. Activity of this protein is important in the epithelial to mesenchymal transition, and over-expression of this gene is implicated in tumor growth and metastasis. Alternative splicing results in multiple transcript variants.
Abbreviation
ILK
UniProt
O55222
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant Mouse ILK protien by E.coli
Target
59 kDa serine/threonine protein kinase;59 kDa serine/threonine-protein kinase; DKFZp686F1765; Epididymis secretory protein Li 28; HEL S 28; ILK 1; ILK 2; ILK; ILK-1; ILK-2; ILK; ILK1; ILK2; Integrin linked kinase 2; Integrin linked Kinase; Integrin linked protein kinase; Integrin-linked protein kinase; p59; p59ILK
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Cancer; Signal Transduction
Purification
Antigen Affinity Purification
Concentration
1 mg/mL
Dilution
IHC 1:400-1:800
Buffer
PBS with 0.02% sodium azide,1% protective protein and 50% glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG

UniProtKB · O55222

Scaffold protein ILK

ILK_MOUSE · Mus musculus

View on UniProt ↗
Primary accession
O55222
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
Ilk
Protein existence
1: Evidence at protein level
Organism
Mus musculus (Mouse)
Taxonomy ID
10090
Alternative names
—
EC number
—
Processing
—
Secondary accessions
Q78KK2
Protein keywords

PTM

AcetylationPhosphoprotein

Domain

ANK repeatRepeat

Ligand

ATP-bindingMagnesiumMetal-bindingNucleotide-binding

Cellular component

Cell junctionCell membraneCell projectionCytoplasmCytoskeletonMembraneNucleus

Technical term

Reference proteome