9-Hydroxycalabaxanthone

• Description :

  9-Hydroxycalabaxanthone (Xanthone I) is a known xanthone isolated from Garcinia mangostana Linn. 9-Hydroxycalabaxanthone has quorum-sensing inhibitory, anti-microbial, and anti-malarial activities (IC50=1.2-1.5 μM) [1].

• Product Name Alternative :

  Xanthone I

• UNSPSC :

  12352005

• Hazard Statement :

  H315, H319

• Target :

  Bacterial; Parasite

• Type :

  Reference compound

• Related Pathways :

  Anti-infection

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Infection

• Assay Protocol :

  https://www.medchemexpress.com/9-hydroxycalabaxanthone.html

• Purity :

  99.14

• Solubility :

  DMSO : 50 mg/mL (ultrasonic)

• Smiles :

  O=C1C2=C(OC3=C1C(C/C=C(C)\C)=C(OC)C(O)=C3)C=C4C(C=CC(C)(C)O4)=C2O

• Molecular Formula :

  C24H24O6

• Molecular Weight :

  408.44

• Precautions :

  H315, H319

• References & Citations :

  [1]Gamal A Mohamed, et al. Mangostanaxanthones I and II, New Xanthones From the Pericarp of Garcinia Mangostana. Fitoterapia. 2014 Oct;98:215-21.|[2]Wanna Chaijaroenkul, et al. The in Vitro Antimalarial Interaction of 9-hydroxycalabaxanthone and α-mangostin With mefloquine/artesunate. Acta Parasitol. 2014 Mar;60 (1) :105-11.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  4°C (Powder, protect from light)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  Plasmodium

• CAS Number :

  [35349-68-9]