9-Hydroxycalabaxanthone

• Description:

  9-Hydroxycalabaxanthone (Xanthone I) is a known xanthone isolated from Garcinia mangostana Linn. 9-Hydroxycalabaxanthone has quorum-sensing inhibitory, anti-microbial, and anti-malarial activities (IC50=1.2-1.5 μM) [1].

• Product Name Alternative:

  Xanthone I

• UNSPSC:

  12352005

• Hazard Statement:

  H315, H319

• Target:

  Bacterial; Parasite

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/9-hydroxycalabaxanthone.html

• Purity:

  99.14

• Solubility:

  DMSO : 50 mg/mL (ultrasonic)

• Smiles:

  O=C1C2=C(OC3=C1C(C/C=C(C)\C)=C(OC)C(O)=C3)C=C4C(C=CC(C)(C)O4)=C2O

• Molecular Formula:

  C24H24O6

• Molecular Weight:

  408.44

• Precautions:

  H315, H319

• References & Citations:

  [1]Gamal A Mohamed, et al. Mangostanaxanthones I and II, New Xanthones From the Pericarp of Garcinia Mangostana. Fitoterapia. 2014 Oct;98:215-21.|[2]Wanna Chaijaroenkul, et al. The in Vitro Antimalarial Interaction of 9-hydroxycalabaxanthone and α-mangostin With mefloquine/artesunate. Acta Parasitol. 2014 Mar;60 (1) :105-11.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, protect from light)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  Plasmodium

• CAS Number:

  [35349-68-9]