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Digeranyl bisphosphonate

CAT: 0804-HY-U00145-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-U00145-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Digeranyl bisphosphonate (DGBP) is a potent geranylgeranylpyrophosphate (GGPP) synthase inhibitor, which inhibits geranylgeranylation of Rac1.
CAS Number
878143-03-4
Product Name Alternative
DGBP
UNSPSC
12352211
Target
Ras
Type
Reference compound
Related Pathways
GPCR/G Protein; MAPK/ERK Pathway
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/Phosphonic_acid,_[_3E_-1-[_2E_-3,7-dimethyl-2,6-octadienyl]-4,8-dimethyl-3,7-nonadienylidene]bis-,_tetrasodium_salt.html
Purity
99.07
Solubility
DMSO : 2 mg/mL (ultrasonic)
Smiles
C/C(C)=C\CC/C(C)=C/CC(P(O[Na])(O[Na])=O)(P(O[Na])(O[Na])=O)C/C=C(C)/CC/C=C(C)\C
Molecular Formula
C21H34Na4O6P2
Molecular Weight
536.40
References & Citations
[1]Osborn-Heaford HL, et al. Targeting the isoprenoid pathway to abrogate progression of pulmonary fibrosis. Free Radic Biol Med. 2015 Sep;86:47-56.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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