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Neochlorogenic acid

CAT: 0804-HY-N0722-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N0722-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Neochlorogenic acid is a natural polyphenolic compound found in dried fruits and other plants. Neochlorogenic acid inhibits the production of TNF-α and IL-1β. Neochlorogenic acid suppresses iNOS and COX-2 protein expression. Neochlorogenic acid also inhibits phosphorylated NF-κB p65 and p38 MAPK activation.
CAS Number
906-33-2
Product Name Alternative
Trans-5-O-Caffeoylquinic acid
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
COX; Interleukin Related; NF-κB; TNF Receptor
Type
Natural Products
Related Pathways
Apoptosis; Immunology/Inflammation; NF-κB
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Cancer
Assay Protocol
https://www.medchemexpress.com/Neochlorogenic-acid.html
Purity
99.80
Solubility
DMSO : 100 mg/mL (ultrasonic) |H2O : 2 mg/mL (ultrasonic)
Smiles
O=C([C@]1(O)C[C@@H](OC(/C=C/C2=CC=C(O)C(O)=C2)=O)[C@@H](O)[C@H](O)C1)O
Molecular Formula
C16H18O9
Molecular Weight
354.31
Precautions
H302, H315, H319, H335
References & Citations
[1]Kim M, et al. Neochlorogenic Acid Inhibits Lipopolysaccharide-Induced Activation and Pro-inflammatory Responses in BV2 Microglial Cells. Neurochem Res. 2015 Sep;40 (9) :1792-8.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
COX-2; IL-1; RelA/p65; TNFRSF5/CD40

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