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Pergolide (mesylate)

CAT: 0804-HY-13720A-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-13720A-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Pergolide mesylate (Pergolide methanesulfonate), an Ergoline derivative, is a potent and orally active dopamine D1 and D2 receptors agonist. Pergolide mesylate can be used for Parkinson's disease and hyperprolactinaemia research[1][2].
CAS Number
66104-23-2
Product Name Alternative
Pergolide methanesulfonate; LY127809
UNSPSC
12352005
Hazard Statement
H300
Target
Dopamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/pergolide-mesylate.html
Purity
99.98
Solubility
DMSO : 50 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
[H][C@@]1(N(CCC)C[C@H](CSC)C[C@@]12[H])CC3=CNC4=CC=CC2=C43.CS(=O)(O)=O
Molecular Formula
C20H30N2O3S2
Molecular Weight
410.59
Precautions
H300
References & Citations
[1]S Franks, et al. Effectiveness of pergolide mesylate in long term treatment of hyperprolactinaemia. Br Med J (Clin Res Ed) . 1983 Apr 9;286 (6372) :1177-9.|[2]Daniela Uberti, et al. Pergolide protects SH-SY5Y cells against neurodegeneration induced by H (2) O (2) . Eur J Pharmacol. 2002 Jan 2;434 (1-2) :17-20.|[3]Alin Ciobica, et al. The effects of pergolide on memory and oxidative stress in a rat model of Parkinson's disease. J Physiol Biochem. 2012 Mar;68 (1) :59-69.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
D1 Receptor; D2 Receptor

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