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CTX1

CAT: 0804-HY-U00442-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-U00442-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CTX1 is a p53 activator that overcomes HdmX-mediated p53 repression. CTX1 exhibits potent anti-cancer activity in a mouse acute myeloid leukemia (AML) model system[1].
CAS Number
501935-96-2
UNSPSC
12352005
Hazard Statement
H315
Target
E1/E2/E3 Enzyme; MDM-2/p53
Type
Reference compound
Related Pathways
Apoptosis; Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/CTX1.html
Purity
98.50
Solubility
DMSO : 12.5 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
N#CC1=C(C=CC(N)=C2)C2=NC3=CC(N)=CC=C31
Molecular Formula
C14H10N4
Molecular Weight
234.26
Precautions
H315
References & Citations
[1]Karan G, et al. Identification of a Small Molecule That Overcomes HdmX-Mediated Suppression of p53. Mol Cancer Ther. 2016 Apr;15 (4) :574-582.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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