CTX-0124143

• Description :

  CTX-0124143 is a KAT6A inhibitor with a sulfonyl hydrazine skeleton[1].

• UNSPSC :

  12352005

• Target :

  Histone Acetyltransferase

• Type :

  Reference compound

• Related Pathways :

  Epigenetics

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/ctx-0124143.html

• Purity :

  98.84

• Solubility :

  DMSO : 125 mg/mL (ultrasonic)

• Smiles :

  O=C(NNS(=O)(C1=CC=C2C=CC=CC2=C1)=O)C3=CC=CC=C3F

• Molecular Formula :

  C17H13FN2O3S

• Molecular Weight :

  344.36

• References & Citations :

  [1]Duan Y, et al. Discovery of N- (2-oxoethyl) sulfanilamide-derived inhibitors of KAT6A (MOZ) against leukemia by an isostere strategy. Eur J Med Chem. 2023 Nov 15;260:115770.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [423731-64-0]