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Corticosterone-d4

CAT: 0804-HY-B1618S1Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B1618S1Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Corticosterone-d4 is the deuterium labeled Corticosterone. Corticosterone is an adrenocortical steroid that has modest but significant activities as a mineralocorticoid and a glucocorticoid.
CAS Number
2243253-91-8
Product Name Alternative
17-Deoxycortisol-d4; 11β,21-Dihydroxyprogesterone-d4; Kendall's compound B-d4
UNSPSC
12352211
Target
Endogenous Metabolite; Glucocorticoid Receptor; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease; Others; Vitamin D Related/Nuclear Receptor
Field of Research
Neurological Disease; Endocrinology
Purity
99.17
Solubility
DMSO : 100mg/mL (ultrasonic) |Ethanol : 14.29mg/mL (ultrasonic) |H2O : < 0.1 mg/mL
Smiles
C[C@@]12[C@@H](C(CO)=O)CC[C@@]1([H])[C@]3([H])CCC4=CC(CC[C@]4(C)[C@@]3([2H])[C@](O)([2H])C2([2H])[2H])=O
Molecular Formula
C21H26D4O4
Molecular Weight
350.49
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Gasser PJ, et al. Corticosterone-sensitive monoamine transport in the rat dorsomedial hypothalamus: potential role for organiccation transporter 3 in stress-induced modulation of monoaminergic neurotransmission. J Neurosci. 2006 Aug 23;26 (34) :8758-8766.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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CS-I-00456Corticosterone-[9,11,12,12-d4]
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