Products for Research Use Only
RegisterLogin

Cefoperazone

CAT: 0804-HY-B0210-03Size: 1 gDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-B0210-03Size:1 g
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Cefoperazone, a semisynthetic cephalosporin, has a broad spectrum of antibacterial activity[1].
CAS Number
62893-19-0
UNSPSC
12352005
Hazard Statement
H317, H334
Target
Antibiotic; Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/cefoperazone.html
Purity
99.82
Solubility
DMSO : ≥ 100 mg/mL|H2O : < 0.1 mg/mL
Smiles
O=C(C(N12)=C(CSC3=NN=NN3C)CS[C@]2([H])[C@H](NC([C@H](NC(N4C(C(N(CC)CC4)=O)=O)=O)C5=CC=C(O)C=C5)=O)C1=O)O
Molecular Formula
C25H27N9O8S2
Molecular Weight
645.67
Precautions
H317, H334
References & Citations
[1]N Matsubara, et al. In vitro antibacterial activity of cefoperazone (T-1551), a new semisynthetic cephalosporin. Antimicrob Agents Chemother. 1979 Dec;16 (6) :731-5.|[2]Pedro H.Di Rocco, et al. Aerosol treatment with cefoperazone or gentamicin protects granulocytopenic mice from acute Pseudomonas aeruginosa pneumonia. European Journal of Pharmaceutical Sciences Volume 1, Issue 6, June 1994, Pages 285-289.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
β-lactam
Citation 01
Carbohydr Polym. 2024 Jan 1:323:121379.|J Antibiot (Tokyo) . 2023 Apr;76 (4) :225-235.|Mol Med. 2024 Nov 6;30 (1) :203.|Toxicol Appl Pharmacol. 2023 Apr 1:464:116447.|Carbohydr Polym. 2024 Jan 1:323:121379.

Chemical Information

Cefoperazone

Cefoperazone is a semi-synthetic parenteral cephalosporin with a tetrazolyl moiety that confers beta-lactamase resistance. It has a role as an antibacterial drug.

CAS Number62893-19-0
PubChem CID44187
IUPAC Name(6R,7R)-7-[[(2R)-2-[(4-ethyl-2,3-dioxopiperazine-1-carbonyl)amino]-2-(4-hydroxyphenyl)acetyl]amino]-3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Molecular FormulaC25H27N9O8S2
Molecular Weight645.7
XLogP-0.7
Topological Polar Surface Area271
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count13
Rotatable Bond Count9
Heavy Atom Count44
Formal Charge0
Complexity1250
SMILES
CCN1CCN(C(=O)C1=O)C(=O)N[C@H](C2=CC=C(C=C2)O)C(=O)N[C@H]3[C@@H]4N(C3=O)C(=C(CS4)CSC5=NN=NN5C)C(=O)O
InChI
InChI=1S/C25H27N9O8S2/c1-3-32-8-9-33(21(39)20(32)38)24(42)27-15(12-4-6-14(35)7-5-12)18(36)26-16-19(37)34-17(23(40)41)13(10-43-22(16)34)11-44-25-28-29-30-31(25)2/h4-7,15-16,22,35H,3,8-11H2,1-2H3,(H,26,36)(H,27,42)(H,40,41)/t15-,16-,22-/m1/s1
InChIKey
GCFBRXLSHGKWDP-XCGNWRKASA-N
Chemical Structure
2D Structure
2D structure of Cefoperazone
CAS: 62893-19-0
CID: 44187
Formula: C25H27N9O8S2
MW: 645.7
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight645.7
XLogP3-0.7
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count13
Rotatable Bond Count9
Exact Mass645.14240120
Monoisotopic Mass645.14240120
Topological Polar Surface Area271 Ų
Heavy Atom Count44
Formal Charge0
Complexity1250
Isotope Atom Count0
Defined Atom Stereocenter Count3
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
HY-106572-01Cefbuperazone
HY-106572ACefbuperazone (sodium)

Alternative Products

CatalogName
MBS3608919-01Cefoperazone

Popular Products