Cefoperazone

• Description:

  Cefoperazone, a semisynthetic cephalosporin, has a broad spectrum of antibacterial activity[1].

• UNSPSC:

  12352005

• Hazard Statement:

  H317, H334

• Target:

  Antibiotic; Bacterial

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/cefoperazone.html

• Purity:

  99.82

• Solubility:

  DMSO : ≥ 100 mg/mL|H2O : < 0.1 mg/mL

• Smiles:

  O=C (C (N12) =C (CSC3=NN=NN3C) CS[C@]2 ([H]) [C@H] (NC ([C@H] (NC (N4C (C (N (CC) CC4) =O) =O) =O) C5=CC=C (O) C=C5) =O) C1=O) O

• Molecular Formula:

  C25H27N9O8S2

• Molecular Weight:

  645.67

• Precautions:

  H317, H334

• References & Citations:

  [1]N Matsubara, et al. In vitro antibacterial activity of cefoperazone (T-1551), a new semisynthetic cephalosporin. Antimicrob Agents Chemother. 1979 Dec;16 (6) :731-5.|[2]Pedro H.Di Rocco, et al. Aerosol treatment with cefoperazone or gentamicin protects granulocytopenic mice from acute Pseudomonas aeruginosa pneumonia. European Journal of Pharmaceutical Sciences Volume 1, Issue 6, June 1994, Pages 285-289.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  Launched

• Isoform:

  β-lactam

• Citation 01:

  Carbohydr Polym. 2024 Jan 1:323:121379.|J Antibiot (Tokyo) . 2023 Apr;76 (4) :225-235.|Mol Med. 2024 Nov 6;30 (1) :203.|Toxicol Appl Pharmacol. 2023 Apr 1:464:116447.|Carbohydr Polym. 2024 Jan 1:323:121379.

• CAS Number:

  62893-19-0