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LGD-6972 (sodium)

CAT: 0804-HY-12525ASize: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-12525ASize:1 Each
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Description
LGD-6972 sodium is a selective and orally active glucagon receptor antagonist. LGD-6972 sodium has the potential for type 2 diabetes research[1].
CAS Number
1207989-22-7
UNSPSC
12352005
Target
GCGR
Type
Reference compound
Related Pathways
GPCR/G Protein
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/lgd-6972-sodium.html
Smiles
O=C(NCCS(=O)(O[Na])=O)C1=CC=C(C[C@H](C2=CC=C(C3=CC=C(C(C)(C)C)C=C3)C=C2)C(NC4=CC=C(C5=C(C)C=C(C)C=C5C)C=C4)=O)C=C1
Molecular Formula
C43H45N2NaO5S
Molecular Weight
724.88
References & Citations
[1]Vajda EG, et al. Pharmacokinetics and pharmacodynamics of single and multiple doses of the glucagon receptor antagonist LGD-6972 in healthy subjects and subjects with type 2 diabetes mellitus. Diabetes Obes Metab. 2017 Jan;19 (1) :24-32.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 1

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