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PTGR2-IN-1

CAT: 0804-HY-122716-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-122716-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PTGR2-IN-1 is a potent PTGR2 inhibitor with an IC50 of ~0.7 μM. PTGR2-IN-1 increases 15-keto-PGE2-dependent PPARγ transcriptional activity in PTGR2-transfected HEK293T cells[1].
CAS Number
349093-44-3
UNSPSC
12352005
Target
PPAR
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/ptgr2-in-1.html
Concentration
10mM
Purity
99.82
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
COC1=CC=CC=C1N2CCN(C(CC3=CC=CC=C3)=O)CC2
Molecular Formula
C19H22N2O2
Molecular Weight
310.39
References & Citations
[1]Parker CG, et al. Ligand and Target Discovery by Fragment-Based Screening in Human Cells. Cell. 2017;168 (3) :527-541.e29.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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