Products for Research Use Only
RegisterLogin

Rutin (hydrate)

CAT: 0804-HY-N0148A-01Size: 500 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-N0148A-01Size:500 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Rutin (Rutoside) hydrate is a flavonoid found in many plants and shows a wide range of biological activities including anti-inflammatory, antidiabetic, antioxidant, neuroprotective, nephroprotective, hepatoprotective and reducing Aβ oligomer activities. Rutin hydrate can cross the blood brain barrier. Rutin hydrate attenuates vancomycin-induced renal tubular cell apoptosis via suppression of apoptosis, mitochondrial dysfunction, and oxidative stress[1][2][3].
CAS Number
207671-50-9
Product Name Alternative
Rutoside (hydrate) ; Quercetin 3-O-rutinoside (hydrate)
UNSPSC
12352005
Hazard Statement
H302
Target
Amyloid-β; Apoptosis; Autophagy; Endogenous Metabolite
Type
Natural Products
Related Pathways
Apoptosis; Autophagy; Metabolic Enzyme/Protease; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Cancer; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/Rutin_hydrate.html
Purity
98.99
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
O=C1C(O[C@H]2[C@@H]([C@H]([C@@H]([C@@H](CO[C@H]3[C@@H]([C@@H]([C@H]([C@H](C)O3)O)O)O)O2)O)O)O)=C(C4=CC=C(O)C(O)=C4)OC5=CC(O)=CC(O)=C15.O.[36/5]
Molecular Formula
C27H3O16.36/5H2O
Molecular Weight
713.04
Precautions
H302
References & Citations
[1]Ghorbani A. Mechanisms of antidiabetic effects of flavonoid rutin. Biomed Pharmacother. 2017;96:305-312.|[2]Habtemariam S. Rutin as a Natural Therapy for Alzheimer's Disease: Insights into its Mechanisms of Action. Curr Med Chem. 2016;23 (9) :860-873.|[3]Xu PX, et al. Rutin improves spatial memory in Alzheimer's disease transgenic mice by reducing Aβ oligomer level and attenuating oxidative stress and neuroinflammation. Behav Brain Res. 2014;264:173-180.|[4]Abdel-Aleem GA, et al. Rutin hydrate ameliorates cadmium chloride-induced spatial memory loss and neural apoptosis in rats by enhancing levels of acetylcholine, inhibiting JNK and ERK1/2 activation and activating mTOR signalling. Arch Physiol Biochem. 2018;124 (4) :367-377.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
Launched
Citation 01
Arch Endocrinol Metab. 2025 Aug 20;69 (4) :e240410.|Cell Death Differ. 2025 Jun;32 (6) :1041-1057.|Neurotoxicology. 2024 Jul 18:S0161-813X (24) 00082-2.|ACS Omega. 2024 Feb 28;9 (10) :11870-11882.|Adv Sci (Weinh) . 2022 Dec;9 (34) :e2203088.|Antioxidants (Basel) . 2023 Nov 7;12 (11) :1974.|Biology (Basel) . 2024 Aug 29;13 (9) :676.|Eur J Pharmacol. 2025 Jul 5:998:177536.|Eur Rev Med Pharmacol Sci. 2025 Sep;29 (9) :425-433.|Food Chem. 2022 May 1:375:131872.|Food Chem. 2023 Mar 30;405 (Pt A) :134807.|Food Chem. 2025 Dec 30:497:146992.|Food Chem. 2025 May 31:489:144992.|Food Funct. 2025 Oct 27;16 (21) :8548-8563.|Food Res Int. 2024 Oct:193:114812.|iScience. 2023 Sep 9;26 (10) :107866.|Neuron. 2025 Jul 23;113 (14) :2280-2296.e8.|Pharmacogn Mag. 2023 Oct 12.|Phytomedicine. 2023 Apr:112:154700.|Phytomedicine. 2025 Sep 15:148:157267.|Regulatory Research and Medicine Evaluation. 2025.|SSRN. 2025 Mar 20.|SSRN. 2025 Oct 6.

Chemical Information

Rutin trihydrate
CAS Number207671-50-9
PubChem CID16218542
IUPAC Name2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxymethyl]oxan-2-yl]oxychromen-4-one;trihydrate
Molecular FormulaC27H36O19
Molecular Weight664.6
Topological Polar Surface Area269
Hydrogen Bond Donor Count13
Hydrogen Bond Acceptor Count19
Rotatable Bond Count6
Heavy Atom Count46
Formal Charge0
Complexity1020
SMILES
C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)OC[C@@H]2[C@H]([C@@H]([C@H]([C@@H](O2)OC3=C(OC4=CC(=CC(=C4C3=O)O)O)C5=CC(=C(C=C5)O)O)O)O)O)O)O)O.O.O.O
InChI
InChI=1S/C27H30O16.3H2O/c1-8-17(32)20(35)22(37)26(40-8)39-7-15-18(33)21(36)23(38)27(42-15)43-25-19(34)16-13(31)5-10(28)6-14(16)41-24(25)9-2-3-11(29)12(30)4-9;;;/h2-6,8,15,17-18,20-23,26-33,35-38H,7H2,1H3;3*1H2/t8-,15+,17-,18+,20+,21-,22+,23+,26+,27-;;;/m0.../s1
InChIKey
NLLBWFFSGHKUSY-JPRRWYCFSA-N
Chemical Structure
2D Structure
2D structure of Rutin trihydrate
CAS: 207671-50-9
CID: 16218542
Formula: C27H36O19
MW: 664.6
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight664.6
Hydrogen Bond Donor Count13
Hydrogen Bond Acceptor Count19
Rotatable Bond Count6
Exact Mass664.18507891
Monoisotopic Mass664.18507891
Topological Polar Surface Area269 Ų
Heavy Atom Count46
Formal Charge0
Complexity1020
Isotope Atom Count0
Defined Atom Stereocenter Count10
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count4
Compound Is CanonicalizedYes

Related Products

CatalogName
HY-N0148-01Rutin
HY-W013075-01Rutin (trihydrate)
HY-W740884Rutin-d3
HY-N0148R-01Rutin (Standard)
HY-W013075RRutin (trihydrate) (Standard)
HY-127018AMaltoheptaose (hydrate)
HY-112467Tivozanib (hydrate)
HY-B0117D-01Tigecycline (hydrate)
HY-N0153ANaringin (hydrate)
HY-N0355-01(+) -Catechin hydrate

Alternative Products

CatalogName
OR03679-01Rutin hydrate
297675-01Rutin, hydrate
M33813-01Rutin hydrate B
N1833-100Rutin

Popular Products