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Rutin (Standard)

CAT: 0804-HY-N0148R-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N0148R-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Rutin (Standard) is the analytical standard of Rutin. This product is intended for research and analytical applications. Rutin (Rutoside) is a flavonoid found in many plants and shows a wide range of biological activities including anti-inflammatory, antidiabetic, antioxidant, neuroprotective, nephroprotective, hepatoprotective and reducing Aβ oligomer activities. Rutin is also a CBR1 inhibitor, which can cross the blood brain barrier. Rutin attenuates vancomycin-induced renal tubular cell apoptosis via suppression of apoptosis, mitochondrial dysfunction, and oxidative stress[1][2][3][4][5].
CAS Number
153-18-4
Product Name Alternative
Rutoside (Standard) ; Quercetin 3-O-rutinoside (Standard)
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Amyloid-β; Apoptosis; Autophagy; Endogenous Metabolite; Reference Standards
Type
Reference Standards
Related Pathways
Apoptosis; Autophagy; Metabolic Enzyme/Protease; Neuronal Signaling; Others
Applications
Neuroscience-Neurodegeneration
Field of Research
Inflammation/Immunology; Cancer
Assay Protocol
https://www.medchemexpress.com/rutin-standard.html
Purity
97.33
Smiles
O=C1C(O[C@H]2[C@@H]([C@H]([C@@H]([C@@H](CO[C@H]3[C@@H]([C@@H]([C@H]([C@H](C)O3)O)O)O)O2)O)O)O)=C(C4=CC=C(O)C(O)=C4)OC5=CC(O)=CC(O)=C15
Molecular Formula
C27H30O16
Molecular Weight
610.52
Precautions
H302, H315, H319, H335
References & Citations
[1]Ghorbani A. Mechanisms of antidiabetic effects of flavonoid rutin. Biomed Pharmacother. 2017;96:305-312.|[2]Habtemariam S. Rutin as a Natural Therapy for Alzheimer's Disease: Insights into its Mechanisms of Action. Curr Med Chem. 2016;23 (9) :860-873.|[3]Xu PX, et al. Rutin improves spatial memory in Alzheimer's disease transgenic mice by reducing Aβ oligomer level and attenuating oxidative stress and neuroinflammation. Behav Brain Res. 2014;264:173-180.|[4]Abdel-Aleem GA, et al. Rutin hydrate ameliorates cadmium chloride-induced spatial memory loss and neural apoptosis in rats by enhancing levels of acetylcholine, inhibiting JNK and ERK1/2 activation and activating mTOR signalling. Arch Physiol Biochem. 2018;124 (4) :367-377.|[5]Carlquist M, et al. Flavonoids as inhibitors of human carbonyl reductase 1. Chem Biol Interact. 2008 Jul 30;174 (2) :98-108.
Shipping Conditions
Room Temperature
Storage Conditions
4°C, sealed storage, away from light and moisture
Scientific Category
Reference Standards

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