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Zorevunensen negative control

CAT: 0804-HY-148410CSize: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-148410CSize:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Zorevunensen (STK-001) negative control is the negative control form of Zorevunensen. Zorevunensen is an antisense oligonucleotide that is intended to increase the level of productive SCN1A mRNA and consequently increase the expression of the sodium channel Nav1.1 protein. Zorevunersen is used for the study of Dravet syndrome[1][2].
Product Name Alternative
STK-001 negative control
UNSPSC
12352208
Target
Sodium Channel
Type
Oligonucleotides
Related Pathways
Membrane Transporter/Ion Channel
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/zorevunensen-negative-control.html
Purity
99.28
Smiles
[Zorevunensennegativecontrol]
References & Citations
[1]Wengert ER, et al. Targeted Augmentation of Nuclear Gene Output (TANGO) of Scn1a rescues parvalbumin interneuron excitability and reduces seizures in a mouse model of Dravet Syndrome. Brain Res. 2022 Jan 15;1775:147743.|[2]Bialer M, et al. Progress report on new antiepileptic drugs: A summary of the Sixteenth Eilat Conference on New Antiepileptic Drugs and Devices (EILAT XVI) : II. Drugs in more advanced clinical development. Epilepsia. 2022 Nov;63 (11) :2883-2910.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Oligonucleotides
Clinical Information
No Development Reported

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