MI-503

MI-503

• CAS Number: 1857417-13-0
• UNSPSC Description: MI-503 is a highly potent and orally bioavailable small molecule inhibitor of the menin-mLL interaction.
• Target Antigen: Epigenetic Reader Domain
• Type: Reference compound
• Related Pathways: Epigenetics
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/MI-503.html
• Solubility: DMSO : 25 mg/mL (ultrasonic)
• Smiles: FC(F)(F)CC(S1)=CC2=C1N=CN=C2NC3CCN(CC4=CC=C(N(CC5=CNN=C5)C(C#N)=C6)C6=C4C)CC3
• Molecular Weight: 564.63
• References & Citations: [1]Borkin D, et al. Pharmacologic inhibition of the Menin-MLL interaction blocks progression of MLL leukemia in vivo. Cancer Cell. 2015 Apr 13;27(4):589-602.
• Shipping Conditions: Room Temperature
• Clinical Information: No Development Reported