Apigenin-d5
CAT:
804-HY-N1201S
Size:
1 mg
Price:
Ask
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Apigenin-d5
- CAS Number: 263711-74-6
- UNSPSC Description: Apigenin-d5 is a deuterated labeled Apigenin[1]. Apigenin (4',5,7-Trihydroxyflavone) is a competitive CYP2C9 inhibitor with a Ki of 2 μM.
- Target Antigen: Autophagy; Cytochrome P450; Endogenous Metabolite; Isotope-Labeled Compounds
- Type: Isotope-Labeled Compounds
- Related Pathways: Autophagy;Metabolic Enzyme/Protease;Others
- Field of Research: Inflammation/Immunology
- Purity: 98.90
- Smiles: OC1=C(C(O)=C2C(C([2H])=C(OC2=C1[2H])C3=CC([2H])=C(C([2H])=C3)O)=O)[2H]
- Molecular Weight: 275.27
- References & Citations: [1]Si D, et al. Mechanism of CYP2C9 inhibition by flavones and flavonols. Drug Metab Dispos. 2009 Mar;37(3):629-34.|[2]Wu K, et al. Inhibitory effects of apigenin on the growth of gastric carcinoma SGC-7901 cells. World J Gastroenterol. 2005 Aug 7;11(29):4461-4.|[3]Yu W, et al. Apigenin Attenuates Adriamycin-Induced Cardiomyocyte Apoptosis via the PI3K/AKT/mTOR Pathway. Evid Based Complement Alternat Med. 2017;2017:2590676.|[4]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.
- Shipping Conditions: Blue Ice
- Storage Conditions: -20°C (Powder, protect from light, stored under nitrogen)
- Clinical Information: No Development Reported