DBCO-NHCO-PEG4-NH-Boc

DBCO-NHCO-PEG4-NH-Boc

• CAS Number: 1255942-12-1
• UNSPSC Description: DBCO-NHCO-PEG4-NH-Boc is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. DBCO-NHCO-PEG4-NH-Boc is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. DBCO-NHCO-PEG4-NH-Boc is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
• Target Antigen: ADC Linker; PROTAC Linkers
• Type: ADC Related
• Related Pathways: Antibody-drug Conjugate/ADC Related;PROTAC
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/dbco-nhco-peg4-nh-boc.html
• Purity: 99.19
• Solubility: 10 mM in DMSO
• Smiles: O=C(OC(C)(C)C)NCCOCCOCCOCCOCCC(NCCC(N1C2=CC=CC=C2C#CC3=CC=CC=C3C1)=O)=O
• Molecular Weight: 623.74
• References & Citations: [1]Kuzmin A, et al. Surface functionalization using catalyst-free azide-alkyne cycloaddition.
• Shipping Conditions: Room Temperature
• Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
• Clinical Information: No Development Reported