Products for Research Use Only
RegisterLogin

DBCO-NHCO-PEG4-acid

CAT: 0804-HY-125541Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-125541Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
DBCO-Amide-PEG5-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. DBCO-Amide-PEG5-acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1]. DBCO-NHCO-PEG4-acid is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
CAS Number
1870899-46-9
UNSPSC
12352203
Hazard Statement
H315-H319-H335
Target
ADC Linker; PROTAC Linkers
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related; PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/dbco-nhco-peg4-acid.html
Solubility
10 mM in DMSO
Smiles
O=C(N1CC2=C(C#CC3=C1C=CC=C3)C=CC=C2)CCNC(CCOCCOCCOCCOCCOCCC(O)=O)=O
Molecular Formula
C32H40N2O9
Molecular Weight
596.67
Precautions
P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501
References & Citations
[1]Vukic Soskic, et al. Method for binding biologically active molecules to surfaces. DE102014215208A1.
Shipping Conditions
Room temperature
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
Cleavable Linker; PEG Linkers

Related Products

CatalogName
HY-124386-01DBCO-NHCO-PEG4-amine
HY-133369DBCO-NHCO-PEG3-acid
HY-133370DBCO-NHCO-PEG7-acid
HY-124386A-01DBCO-NHCO-PEG4-amine (TFA)
HY-111456DBCO-NHCO-PEG4-NHS ester
HY-126884-01DBCO-NHCO-PEG4-NH-Boc
HY-140270DBCO-NHCO-PEG13-acid
HY-133373DBCO-NHCO-PEG6-maleimide
HY-133366DBCO-NHCO-PEG2-amine
HY-133367DBCO-NHCO-PEG6-amine

Alternative Products

CatalogName
T15061-01DBCO-NHCO-PEG4-acid
GTR19226791-01DBCO-NHCO-PEG4-amine
BA2584-50DBCO-NHCO-PEG4-NH-Boc
572261DBCO-NHCO-PEG4-NHS ester
GTR19275369-01DBCO-NHCO-PEG4-amine TFA
VZC89946DBCO-NHCO-PEG5-acid
T17773-01DBCO-NHCO-PEG7-acid
T17768-01DBCO-NHCO-PEG3-acid
T17761-01DBCO-NHCO-PEG13-acid

Popular Products