2′-Hydroxy-2,3-dimethoxychalcone

• UNSPSC Description:

  α-Gracinoic acid is a Chalcone (HY-121054) derivative with anti-inflammatory activity. α-Gracinoic acid inhibits nitric oxide production catalyzed by inducible nitric oxide synthase (iNOS) in lipopolysaccharide (LPS)-treated RAW 264.7 cells[1].

• Target Antigen:

  NO Synthase

• Type:

  Reference compound

• Related Pathways:

  Immunology/Inflammation

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/2-hydroxy-2-3-dimethoxychalcone.html

• Smiles:

  O=C(C1=C(O)C=CC=C1)/C=C/C2=C(OC)C(OC)=CC=C2

• Molecular Weight:

  284.31

• References & Citations:

  [1]Kim, et al. "Anti-inflammatory activity of the synthetic chalcone derivatives: inhibition of inducible nitric oxide synthase-catalyzed nitric oxide production from lipopolysaccharide-treated RAW 264.7 cells." Biological and Pharmaceutical Bulletin 30.8 (2007): 1450-1455.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  42220-80-4