TRPV2-selective blocker 1
CAT:
804-HY-157131-05
Size:
50 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
TRPV2-selective blocker 1
- CAS Number: 2242724-49-6
- UNSPSC Description: TRPV2-selective blocker 1 (compound IV2-1) is a selective TRPV2 channel blocker with an IC50 of 6.3 μM. TRPV2-selective blocker 1 does not affect TRPV1, TRPV3 or TRPV4 channels. TRPV2-selective blocker 1 also inhibits TRPV2-mediated Ca2+ influx in macrophages, and inhibits macrophage phagocytosis[1].
- Target Antigen: TRP Channel
- Type: Reference compound
- Related Pathways: Membrane Transporter/Ion Channel;Neuronal Signaling
- Applications: Neuroscience-Neuromodulation
- Field of Research: Neurological Disease
- Assay Protocol: https://www.medchemexpress.com/trpv2-selective-blocker-1.html
- Solubility: DMSO : 100 mg/mL (ultrasonic)
- Smiles: CC(CC(C)/C(C1=CC=CC=C1)=C2SCCS\2)=O
- Molecular Weight: 278.43
- References & Citations: [1]Rick Raudszus, et al. Pharmacological inhibition of TRPV2 attenuates phagocytosis and lipopolysaccharide-induced migration of primary macrophages. Br J Pharmacol. 2023 Nov;180(21):2736-2749.
- Shipping Conditions: Blue Ice
- Clinical Information: No Development Reported