SPP

SPP

• Product Name Alternative: N-succinimidyl 4-(2-pyridyldithio) pentanoate
• CAS Number: 341498-08-6
• UNSPSC Description: SPP (N-succinimidyl 4-(2-pyridyldithio) pentanoate) is a cleavable disulfide linker, can be used to form cytotoxic compound- linker conjugate[1].
• Target Antigen: ADC Linker
• Type: ADC Related
• Related Pathways: Antibody-drug Conjugate/ADC Related
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/spp.html
• Purity: 97.65
• Solubility: DMSO : 100 mg/mL (ultrasonic)
• Smiles: CC(SSC1=NC=CC=C1)CCC(ON2C(CCC2=O)=O)=O
• Molecular Weight: 340.426
• References & Citations: [1]Widdison W, et al. Metabolites of antibody-maytansinoid conjugates: characteristics and in vitro potencies. Mol Pharm. 2015 Jun 1;12(6):1762-73.
• Shipping Conditions: Blue Ice
• Storage Conditions: -20°C, 3 years (Powder)
• Clinical Information: No Development Reported