PDE4B-IN-2
CAT:
804-HY-115687-02
Size:
10 mM / 1 mL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
PDE4B-IN-2
- Product Name Alternative: EPZ015866; GSK3203591
- CAS Number: 915082-52-9
- UNSPSC Description: PDE4B-IN-2 is an orally active and selective PDE4B inhibitor with an IC50 of 15 nM. PDE4B-IN-2 inhibits PDE4D (IC50=1.7 μM). PDE4B-IN-2 exhibits potent anti-inflammatory effects[1].
- Target Antigen: Phosphodiesterase (PDE)
- Type: Reference compound
- Related Pathways: Metabolic Enzyme/Protease
- Field of Research: Inflammation/Immunology
- Assay Protocol: https://www.medchemexpress.com/pde4b-in-2.html
- Purity: 99.21
- Solubility: DMSO : 25 mg/mL (ultrasonic;warming;heat to 60°C)
- Smiles: O=C(O)CC1=CC=C(NC2=NC(C3=CC=C(Cl)S3)=NC(C)=C2CC)C=C1
- Molecular Weight: 387.88
- References & Citations: [1]Kenji Naganuma, et al. Discovery of selective PDE4B inhibitors. Bioorg Med Chem Lett. 2009 Jun 15;19(12):3174-6.
- Shipping Conditions: Room Temperature
- Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
- Clinical Information: No Development Reported