[DAla4] Substance P (4-11)

[DAla4] Substance P (4-11)

• CAS Number: 81381-50-2
• UNSPSC Description: [DAla4] Substance P (4-11) is an analog of Substance P (Substance P (HY-P0201)) that inhibits the binding of 125I-Bolton Hunter-conjugated Eledoisin (Eledoisin (HY-P0006)) (IC50 of 0.5 μM) and 125I-Bolton Hunter-conjugated Substance P (IC50 of 0.15 μM) to rat brain cortex membranes[1].
• Target Antigen: Neurokinin Receptor
• Type: Peptides
• Related Pathways: GPCR/G Protein;Neuronal Signaling
• Applications: Neuroscience-Neuromodulation
• Field of Research: Neurological Disease
• Assay Protocol: https://www.medchemexpress.com/dala4-substance-p-4-11.html
• Solubility: 10 mM in DMSO
• Smiles: CSCC[C@@H](C(N)=O)NC([C@H](CC(C)C)NC(CNC([C@H](CC1=CC=CC=C1)NC([C@@H](NC([C@H](CCC(N)=O)NC([C@H](CCC(N)=O)NC([C@H](N)C)=O)=O)=O)CC2=CC=CC=C2)=O)=O)=O)=O
• Molecular Weight: 940.12
• References & Citations: [1]M A Cascieri, et al. Demonstration of two distinct tachykinin receptors in rat brain cortex. J Biol Chem. 1985 Feb 10;260(3):1501-7.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported