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Fenitrothion-d6

CAT: 0804-HY-B1885S-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B1885S-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Fenitrothion-d6 is the deuterium labeled Fenitrothion. Fenitrothion is a broad-spectrum and orally active insecticide/acaricide. Fenitrothion inhibits cholinesterase, AMPKα and IRS1/PI3K/AKT. Fenitrothion causes Apoptosis, reduces SOD activity. Fenitrothion shows insecticidal effect against Rhyzopertha dominica and Tribolium castaneum adults. Fenitrothion is widely used in cotton crops, vegetable crops, fruit crops and field crops, especially rice. Fenitrothion can be used for brain and spleen toxicology studies[1][2][3][4][5][6][7][8].
CAS Number
203645-59-4
UNSPSC
12352005
Target
Akt; AMPK; Apoptosis; Cholinesterase (ChE) ; Insecticide; Isotope-Labeled Compounds; PI3K; SOD
Type
Isotope-Labeled Compounds
Related Pathways
Apoptosis; Epigenetics; Immunology/Inflammation; Neuronal Signaling; Others; PI3K/Akt/mTOR
Applications
COVID-19-immunoregulation
Field of Research
Infection
Solubility
10 mM in DMSO
Smiles
[2H]C([2H])([2H])OP(OC1=CC(C)=C(C=C1)[N+]([O-])=O)(OC([2H])([2H])[2H])=S
Molecular Formula
C9H6D6NO5PS
Molecular Weight
283.27
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.|[2]Abdel-Ghany R, et al. Impact of Exposure to Fenitrothion on Vital Organs in Rats. J Toxicol. 2016;2016:5609734.|[3]Qing Hong, et al. A microcosm study on bioremediation of fenitrothion-contaminated soil using Burkholderia sp. FDS-1. International Biodeterioration & Biodegradation
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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