GIC-20

• Description :

  GIC-20 is a dual inducer for apoptosis and ferroptosis. GIC-20 exhibits antitumor efficacy against fibrosarcoma[1].

• UNSPSC :

  12352005

• Target :

  Apoptosis; Ferroptosis

• Type :

  Reference compound

• Related Pathways :

  Apoptosis

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/gic-20.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C1C=C(NCCCCCC(NC2=CC=C(N(C(C(NCCC3=CC=CC=C3)=O)C4=CC=CS4)C(CCl)=O)C=C2)=O)C(C5=CC=CC=C51)=O

• Molecular Formula :

  C38H37ClN4O5S

• Molecular Weight :

  697.24

• References & Citations :

  [1]Ma F, et al., ML162 derivatives incorporating a naphthoquinone unit as ferroptosis/apoptosis inducers: Design, synthesis, anti-cancer activity, and drug-resistance reversal evaluation. Eur J Med Chem. 2024 Apr 15;270:116387.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [2942242-60-4]