α-Conotoxin GIC

• Target:

  AChR

• Related Pathways:

  Neuroscience

• Bioactivity:

  ?-Conotoxin GIC is a selective and potent antagonist of the ?3?2 nicotinic acetylcholine receptor, exhibiting an inhibition constant (IC50) of 1.1 nM [1].

• Smiles:

  O=C1N2[C@@] (CCC2) (C (=O) N[C@@H] (C) C (=O) N[C@@]3 (C (=O) N[C@@H] (C) C (=O) NCC (=O) N[C@@H] (CC (N) =O) C (=O) N[C@@H] (CC (N) =O) C (=O) N[C@@H] (CCC (N) =O) C (=O) N[C@@H] (CC4=CN=CN4) C (=O) N[C@@] ([C@H] (CC) C) (C (=O) N[C@H] (C (N) =O) CSSC[C@@] (C (=O) N[C@@H] (CO) C (=O) N[C@H]1CC5=CN=CN5) (NC (=O) [C@@H] (NC (CN) =O) CSSC3) [H]) [H]) [H]) [H]

• Molecular Formula:

  C61H92N24O20S4

• Molecular Weight:

  1609.79

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  757236-92-3