dTAGV-1 (hydrochloride)

dTAGV-1 (hydrochloride)

• CAS Number: 2624313-16-0
• UNSPSC Description: dTAGV-1 hydrochloride is the hydrochloride form of dTAGV-1 that is a small molecule degrader of FKBP12[1].
• Target Antigen: FKBP; PROTACs
• Type: Reference compound
• Related Pathways: Apoptosis;Autophagy;Cell Cycle/DNA Damage;Immunology/Inflammation;PROTAC
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/dtagv-1-hydrochloride.html
• Solubility: DMSO : 100 mg/mL (ultrasonic)
• Smiles: O=C([C@H]1N(CCCC1)C([C@H](C2=CC(OC)=C(C(OC)=C2)OC)CC)=O)O[C@@H](C3=C(C=CC=C3)OCC(NCCCCCCC(N[C@@H](C(C)(C)C)C(N4[C@@H](C[C@H](C4)O)C(N[C@H](C5=CC=C(C6=C(C)N=CS6)C=C5)C)=O)=O)=O)=O)CCC7=CC(OC)=C(C=C7)OC.Cl
• Molecular Weight: 1284.00
• References & Citations: [1]Gray NS, et al. SMALL MOLECULE DEGRADERS OF FKBP12 VIA RECRUITMENT OF VON HIPPEL-LINDAU E3 UBIQUITIN LIGASE (VHL) E3 UBIQUITIN LIGASE, AND USES IN dTAG SYSTEMS. France, WO2020146250A1. 2020-07-16.
• Shipping Conditions: Room Temperature
• Clinical Information: No Development Reported