1-Methylguanidine (hydrochloride)

• UNSPSC Description:

  1-Methylguanidine hydrochloride is a uremic toxin, which accumulate in dogs with renal failure and chronic kidney disese. 1-Methylguanidine hydrochloride enhances the oxidative metabolism and induces apoptosis in neutrophils[1].

• Target Antigen:

  Endogenous Metabolite

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/1-methylguanidine-hydrochloride-1.html

• Smiles:

  NC(NC)=N.[x].Cl

• References & Citations:

  [1]Bosco AM, et al., The uremic toxin methylguanidine increases the oxidative metabolism and accelerates the apoptosis of canine neutrophils. Vet Immunol Immunopathol. 2017 Mar;185:14-19.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  22661-87-6