Arecoline (hydrobromide)
CAT:
804-HY-B0489-03
Size:
500 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Arecoline (hydrobromide)
- CAS Number: 300-08-3
- UNSPSC Description: Arecoline hydrobromide, a naturally occurring psychoactive alkaloid, is a partial agonist of nicotinic and muscarinic acetylcholine receptor. Arecoline hydrobromide exhibits stimulation, alertness, anxiolysis and anti-parasitic effects. Arecoline hydrobromide also can induce oxidative stress[1][2][3][4].
- Target Antigen: mAChR; nAChR
- Type: Natural Products
- Related Pathways: GPCR/G Protein;Membrane Transporter/Ion Channel;Neuronal Signaling
- Applications: Neuroscience-Neuromodulation
- Field of Research: Cancer; Infection; Metabolic Disease; Inflammation/Immunology; Neurological Disease
- Assay Protocol: https://www.medchemexpress.com/Arecoline-hydrobromide.html
- Purity: 99.95
- Solubility: DMSO : ≥ 50 mg/mL|H2O : 50 mg/mL (ultrasonic)
- Smiles: O=C(C1=CCCN(C)C1)OC.Br
- Molecular Weight: 236.11
- References & Citations: [1]Thangjam GS, et, al. Regulation of oxidative-stress responsive genes by arecoline in human keratinocytes. J Periodontal Res. 2009 Oct;44(5):673-82.|[2]Liu YJ, et, al. The pharmacology, toxicology and potential applications of arecoline: a review. Pharm Biol. 2016 Nov;54(11):2753-2760.|[3]Volgin AD, et, al. DARK Classics in Chemical Neuroscience: Arecoline. ACS Chem Neurosci. 2019 May 15;10(5):2176-2185. |[4]Kuo TM, et, al. Arecoline induces TNF-alpha production and Zonula Occludens-1 redistribution in mouse Sertoli TM4 cells. J Biomed Sci. 2014 Sep 9;21(1):93.J Oral Pathol Med. 2022 Sep 2.|Int J Mol Sci. 2023 Mar 28.
- Shipping Conditions: Room Temperature
- Storage Conditions: 4°C (Powder, sealed storage, away from moisture)
- Clinical Information: No Development Reported