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IRAP-IN-1

CAT: 0804-HY-163714Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-163714Size:1 Each
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Description
IRAP-IN-1 (compound 3) is a potent and selective insulin regulated aminopeptidase (IRAP) inhibitor with an IC50 value of 157 nM[1].
UNSPSC
12352005
Target
Aminopeptidase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/irap-in-1.html
Smiles
O=C(N(C)CC1=CC=CN=C1C)COC2=NC(N3N=C(C)C=C3C)=NC(C4=CC=C(OC)C=C4)=C2
Molecular Formula
C26H28N6O3
Molecular Weight
472.54
References & Citations
[1]Anastasia Mpakali, et al.Stabilization of the open conformation of Insulin-Regulated Aminopeptidase by a novel substrate-selective small molecule inhibitor. Biorxiv, 2024.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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