IRAK inhibitor 1
CAT:
804-HY-13275-04
Size:
10 mM / 1 mL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
IRAK inhibitor 1
- CAS Number: 1042224-63-4
- UNSPSC Description: IRAK inhibitor 1 is a potent IRAK-4 inhibitor with IC50 of 216 nM, is poorly active against JNK-1 and JNK-2 with IC50 of 3.801 μM, and >10 μM, respectively.
- Target Antigen: IRAK
- Type: Reference compound
- Related Pathways: Immunology/Inflammation
- Field of Research: Inflammation/Immunology
- Assay Protocol: https://www.medchemexpress.com/IRAK-inhibitor-1.html
- Purity: 99.83
- Solubility: DMSO : 16.67 mg/mL (ultrasonic)
- Smiles: C1(C2=CN=C3N2C=CC=C3)=CC=CC(NC4CCNCC4)=N1
- Molecular Weight: 293.37
- References & Citations: [1]Buckley GM, et al. IRAK-4 inhibitors. Part II: A structure-based assessment of imidazo[1,2-a]pyridine binding. Bioorg Med Chem Lett. 2008 Jun 1;18(11):3291-5.|[2]Li S, et al. IRAK-4: a novel member of the IRAK family with the properties of an IRAK-kinase. Proc Natl Acad Sci U S A. 2002 Apr 16;99(8):5567-72.
- Shipping Conditions: Room Temperature
- Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
- Clinical Information: No Development Reported