SARS-CoV-2 3CLpro probe-1

• UNSPSC Description:

  SARS-CoV-2 3CLpro probe-1 (Compound probe 3) is a selective and activity-based probe for the SARS-CoV-2 3CL protease. SARS-CoV-2 3CLpro probe-1 can detect endogenously expressed 3CLpro in SARS-CoV-2-infected cells[1].

• Target Antigen:

  Fluorescent Dye

• Type:

  Dye Reagents

• Related Pathways:

  Others

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/sars-cov-2-3clpro-probe-1.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(N[C@@H](CC(C)C)C(N[C@@H](C[C@@H]1CCNC1=O)C(COC(C2=C(Cl)C=CC=C2Cl)=O)=O)=O)C3=CC(C(OCC#C)=CC=C4)=C4N3

• Molecular Weight:

  669.55

• References & Citations:

  [1]Yamauchi Y, et al. Detection of Active SARS-CoV-2 3CL Protease in Infected Cells Using Activity-Based Probes with a 2,6-Dichlorobenzoyloxymethyl Ketone Reactive Warhead. ACS Chem Biol. 2024;19(5):1028-1034.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported