Tolcapone 3-β-D-glucuronide

Tolcapone 3-β-D-glucuronide

• CAS Number: 204853-33-8
• UNSPSC Description: Tolcapone 3-β-D-glucuronide (Ro 61-1448) is an O-methyl metabolite and the glucuronide metabolite of Tolcapone (Ro 40-7592; HY-17406). Tolcapone 3-β-D-glucuronide is pharmacologically inactive[1].
• Target Antigen: Drug Metabolite
• Type: Natural Products
• Related Pathways: Metabolic Enzyme/Protease
• Applications: Metabolism-protein/nucleotide metabolism
• Field of Research: Others
• Assay Protocol: https://www.medchemexpress.com/tolcapone-3-β-d-glucuronide.html
• Smiles: O[C@@H]1[C@@H](O)[C@H](O)[C@H](O[C@H]1OC2=CC(C(C3=CC=C(C=C3)C)=O)=CC([N+]([O-])=O)=C2O)C(O)=O
• Molecular Weight: 449.36
• References & Citations: [1]P Heizmann, et al. Determination of the catechol-O-methyltransferase inhibitor tolcapone and three of its metabolites in animal and human plasma and urine by reversed-phase high-performance liquid chromatography with ultraviolet detection. J Chromatogr B Biomed Sci Appl. 1999 Jul 9;730(2):153-60.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported