Kaempferol 3-O-β-D-glucuronide

• UNSPSC Description:

  Kaempferol 3-O-β-D-glucuronide (Kaempferol-3-glucuronide) is a metabolite of kaempferol that can be taken orally and has anti-inflammatory properties. Kaempferol 3-O-β-D-glucuronide can activate AKT/GSK3β phosphorylation and improve glucose metabolism[1][2][3].

• Target Antigen:

  Interleukin Related

• Type:

  Natural Products

• Related Pathways:

  Immunology/Inflammation

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Cancer; Metabolic Disease; Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/kaempferol-3-o-β-d-glucuronide.html

• Purity:

  99.41

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  O[C@H]([C@H]([C@@H]([C@@H](C(O)=O)O1)O)O)[C@@H]1OC2=C(C3=CC=C(O)C=C3)OC4=CC(O)=CC(O)=C4C2=O

• Molecular Weight:

  462.36

• References & Citations:

  [1]Khajuria V, et al. Kaempferol-3-o-β-d-glucuronate exhibit potential anti-inflammatory effect in LPS stimulated RAW 264.7 cells and mice model. Int Immunopharmacol. 2018;57:62-71.|[2]Rupayan Bhattacharjee, et al. Extraction and Characterization of Flavonoid Kaempferol-3-Glucuronide from Mango for Treatment of Different Types of Cancers. Great Britain Journals Press. Print ISSN: 2631-8490|[3]Ge Fang, et al. The glucuronide metabolites of kaempferol and quercetin, targeting to the AKT PH domain, activate AKT/GSK3β signaling pathway and improve glucose metabolism. Journal of Functional Foods. Volume 82, July 2021, 104501.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, protect from light)

• Clinical Information:

  No Development Reported

• CAS Number:

  22688-78-4