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Substance P (1-4)

CAT: 0804-HY-P3598Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-P3598Size:1 Each
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Description
Substance P (1-4) is a potent neurokinin receptors (NK-R) antagonist. Substance P (1-4) has regulation of normal hematopoiesis and inhibits endogenous erythroid colony (EEC) formation[1].
CAS Number
57468-16-3
UNSPSC
12352209
Target
Neurokinin Receptor
Type
Peptides
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/substance-p-1-4.html
Solubility
10 mM in DMSO
Smiles
O=C(N1[C@@H](CCC1)C(O)=O)[C@H](CCCCN)NC([C@H]2N(CCC2)C([C@@H](N)CCCNC(N)=N)=O)=O
Molecular Formula
C22H40N8O5
Molecular Weight
496.60
References & Citations
[1]Le Gall C, et, al. Inhibitory effect of the substance P and its derivative on erythropoietin-independent growth of erythroid progenitors in polycythemia vera. Leuk Res. 2008 May;32 (5) :743-54.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported