Anti-CD45 LCA

CAT: 0171-Y300116Size: 100 µLDry Ice: NoHazardous: No
CAT#:0171-Y300116Size:100 µL
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Encoded by the gene PTPRC, CD45 is a member of the protein tyrosine phosphatase (PTP) family. It is required for T-cell activation through the antigen receptor. It serves as a positive regulator of T-cell co-activation upon binding to DPP4 and recruits and dephosphorylates SKAP1 and FYN upon T-cell activation. Mutations in the PTPRC gene is associated with diseases including severe combined immunodeficiency (SCID), and hepatitis C. CD45 is useful as a marker to recognize different stem cells such as mesenchymal stem cells and hematopoietic stem cells.
CAS Number
9007-83-4
Reactivity
Human
Immunogen
Human T lymphocytes
Clonality
Monoclonal
Type
Antibodies-Monoclonal
Applications
WB,IHC,IP
Concentration
100µg/100µl
Purity
The antibody was affinity-purified from hybridoma supernatant by affinity-chromatography.
Buffer
PBS, pH 7.4 with 0.05% sodium azide
Shipping Conditions
Ice Pack
Storage Conditions
This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Fragment
IgG2a
Specificity
Human CD45 determinant 1
Applications Notes
WB: 1:1000; IP: Use at an assay dependent concentration; IHC: 1:500~1:1000. Optimal dilutions should be calculated by the end user based on their specific application.

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