Anti-CD44

• Description:

  CD44 is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA), and their interaction plays an important role in cell migration, tumor growth and progression. CD44 can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. It may play an important role in invadopodia formation in cancer cell. Altered expression or dysfunction of this protein is shown to cause numerous pathogenic phenotypes.

• Reactivity:

  Human,Other

• Immunogen:

  Human lymphoid cells

• Clonality:

  Monoclonal

• Type:

  Antibodies-Monoclonal

• Applications:

  WB,IHC,ICC/IF

• Concentration:

  100µg/100µl

• Purity:

  The antibody was affinity-purified from hybridoma supernatant by affinity-chromatography.

• Buffer:

  PBS, pH 7.4 with 0.05% sodium azide

• Shipping Conditions:

  Ice Pack

• Storage Conditions:

  This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.

• Fragment:

  IgG2a

• Specificity:

  Human CD44

• Applications Notes:

  WB: 1:2000~1:5000 IHC: 1:200~1:500 IF: 1:200~1:500 Optimal dilutions should be calculated by the end user based on their specific application.

• CAS Number:

  9007-83-4