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Anti-mTOR (Ab-2448)

CAT: 0171-Y021214Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0171-Y021214Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
The protein encoded by this gene belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. The ANGPTL7 gene is located in an intron of this gene. [provided by RefSeq, Sep 2008]
CAS Number
9007-83-4
Reactivity
Human,Mouse,Rat
Immunogen
The antibody was produced against synthesized non-phosphopeptide derived from human mTOR around the phosphorylation site of serine 2448 (T-D-SP-Y-S).
Clonality
Polyclonal
Type
Antibodies-Polyclonal
Applications
WB,IHC,IP
Concentration
100ug/100ul
Purity
Affinity purified
Buffer
Rabbit IgG in phosphate buffered saline (without Mg<sup>2</sup>+ and Ca<sup>2</sup>+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Shipping Conditions
Ice Pack
Storage Conditions
This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Fragment
IgG
Specificity
mTOR (Ab-2448) Antibody detects endogenous levels of total mTOR protein.
Applications Notes
WB: 1:500~1:1000 IHC: 1:50~1:100 IF:1:100~1:200