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Spermine-d20

CAT: 0804-HY-W654342-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-W654342-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Spermine-d20 (NSC 268508-d20) is deuterium labeled Spermine. Spermine (NSC 268508) functions directly as a free radical scabenger to protect DNA from free radical attack. Spermine has antiviral effects[1].
Product Name Alternative
NSC 268508-d20; Neuridine-d20
UNSPSC
12352211
Target
Endogenous Metabolite; Influenza Virus; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Anti-infection; Metabolic Enzyme/Protease; Others
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Infection; Metabolic Disease; Cancer
Purity
98.47
Smiles
NC([2H])(C([2H])(C([2H])(NC([2H])(C([2H])(C([2H])(C([2H])(NC([2H])(C([2H])(C([2H])(N)[2H])[2H])[2H])[2H])[2H])[2H])[2H])[2H])[2H])[2H]
Molecular Formula
C10H6D20N4
Molecular Weight
222.46
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]Ha HC, et al. The natural polyamine spermine functions directly as a free radical scavenger. Proc Natl Acad Sci U S A. 1998 Sep 15;95 (19) :11140-5.|[3]Mounce BC, et al. Polyamines and Their Role in Virus Infection. Microbiol Mol Biol Rev. 2017 Sep 13;81 (4) . pii: e00029-17.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported