Spermine-d20

• UNSPSC Description:

  Spermine-d20 (NSC 268508-d20) is deuterium labeled Spermine. Spermine (NSC 268508) functions directly as a free radical scabenger to protect DNA from free radical attack. Spermine has antiviral effects[1].

• Target Antigen:

  Endogenous Metabolite; Influenza Virus; Isotope-Labeled Compounds

• Type:

  Isotope-Labeled Compounds

• Related Pathways:

  Anti-infection;Metabolic Enzyme/Protease;Others

• Field of Research:

  Infection;Metabolic Disease;Cancer

• Smiles:

  NC([2H])(C([2H])(C([2H])(NC([2H])(C([2H])(C([2H])(C([2H])(NC([2H])(C([2H])(C([2H])(N)[2H])[2H])[2H])[2H])[2H])[2H])[2H])[2H])[2H])[2H]

• Molecular Weight:

  222.46

• References & Citations:

  [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.|[2]Ha HC, et al. The natural polyamine spermine functions directly as a free radical scavenger. Proc Natl Acad Sci U S A. 1998 Sep 15;95(19):11140-5.|[3]Mounce BC, et al. Polyamines and Their Role in Virus Infection. Microbiol Mol Biol Rev. 2017 Sep 13;81(4). pii: e00029-17.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported