Spermine-d20

• Description:

  Spermine-d20 (NSC 268508-d20) is deuterium labeled Spermine. Spermine (NSC 268508) functions directly as a free radical scabenger to protect DNA from free radical attack. Spermine has antiviral effects[1].

• Product Name Alternative:

  NSC 268508-d20; Neuridine-d20

• UNSPSC:

  12352211

• Target:

  Endogenous Metabolite; Influenza Virus; Isotope-Labeled Compounds

• Type:

  Isotope-Labeled Compounds

• Related Pathways:

  Anti-infection; Metabolic Enzyme/Protease; Others

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Infection; Metabolic Disease; Cancer

• Purity:

  98.47

• Smiles:

  NC([2H])(C([2H])(C([2H])(NC([2H])(C([2H])(C([2H])(C([2H])(NC([2H])(C([2H])(C([2H])(N)[2H])[2H])[2H])[2H])[2H])[2H])[2H])[2H])[2H])[2H]

• Molecular Formula:

  C10H6D20N4

• Molecular Weight:

  222.46

• References & Citations:

  [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]Ha HC, et al. The natural polyamine spermine functions directly as a free radical scavenger. Proc Natl Acad Sci U S A. 1998 Sep 15;95 (19) :11140-5.|[3]Mounce BC, et al. Polyamines and Their Role in Virus Infection. Microbiol Mol Biol Rev. 2017 Sep 13;81 (4) . pii: e00029-17.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C, 3 years (Powder)

• Scientific Category:

  Isotope-Labeled Compounds

• Clinical Information:

  No Development Reported