Recombinant Mouse MCP-5 (CCL12)

Recombinant Mouse MCP-5 (CCL12)

• Description: MCP-5 (CCL12) is a chemotactic factor that attracts eosinophils, monocytes, and lymphocytes but not neutrophils. It is also a potent active monocyte chemokine that signals through CCR2. It is Involved in allergic inflammation and the host response to pathogens. Also, it may play a pivotal role during early stages of allergic lung inflammation.
• CAS Number: 9000-83-3
• Gene Name: CCL12
• Gene Aliases: MCP-1-related chemokine, Monocyte chemotactic protein 5, MCP5, Small-inducible cytokine A12, C-C motif chemokine 12, Mcp5, Scya12
  Recombinant Mouse Monocyte Chemoattractant Protein-5 (CCL12)
• Gene ID: 20293
• Accession Number: Q62401
• Organism: Mouse
• Source: E. coli
• Concentration: <1.0 EU/μg of recombinant protein as determined by the LAL method.
• Purity: >95% as determined by SDS-PAGE
• Solubility: A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.
• Function: Determined by its ability to chemoattract human monocytes using a concentration range of 20-40 ng/mL.
• Molecular Weight: 10
• Shipping Conditions: Ambient Temperature
• Storage Conditions: The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.
• Appearance: Lyophilized Powder
• Formulation: Recombinant MCP-5 was lyophilized from a 0.2 μm filtered 20 mM PB solution pH 7.5, 100 mM NaCl.