Recombinant Mouse IL2
CAT:
171-Z200135
Size:
20 µg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Recombinant Mouse IL2
- Description: IL-2 is produced mainly by T cells expressing the surface antigen CD4 following cell activation by mitogens or allogen. Interleukin-2 (IL-2) has multiple, sometimes opposing, functions during an inflammatory response. It is a potent inducer of T cell proliferation and Th1 and Th2 effector T cell differentiation and provides T cells with a long-lasting competitive advantage resulting in the optimal survival and function of memory cells. In a regulatory role, IL-2 is important for the development, survival, and function of regulatory T cells, it enhances Fas-mediated activation-induced cell death, and it inhibits the development of inflammatory Th17 cells. Thus, in its dual and contrasting functions, IL-2 contributes to both the induction and the termination of inflammatory immune responses.
- CAS Number: 9000-83-3
- Gene Name: IL2
- Gene Aliases: IL-2, T-cell growth factor, TCGF
Recombinant Mouse Interleukin-2 (IL2) - Gene ID: 16183
- Accession Number: P04351
- Organism: Mouse
- Source: E. coli
- Concentration: <1.0 EU/μg of recombinant protein as determined by the LAL method.
- Purity: >95% as determined by SDS-PAGE
- Solubility: A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.
- Function: The ED50 as determined by the dose dependent stimulation of murine CTLL-2 cells is < 0.1 ng/mL, corresponding to a specific activity of > 1 x 107 units/mg.
- Molecular Weight: 17
- Shipping Conditions: Ambient Temperature
- Storage Conditions: The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.
- Appearance: Lyophilized Powder
- Formulation: Recombinant mouse IL-2 was lyophilized from 0.2 μm filtered PBS solution, pH 7.0.