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Recombinant Human TNFRSF1B

CAT: 0171-Z101749Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0171-Z101749Size:1 mg
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Description
TNFRSF1B is a single-pass type-1 transmembrane protein that functions as a receptor with high affinity for TNFSF2/TNF-alpha . It has been shown that signaling through this receptor regulates various biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, coagulation, and neurotransmission. Recombinant human TNFRSF1B comprises the extracellular domain (ligand binding) of the TNFRII protein.
CAS Number
9000-83-3
Gene Name
TNFRSF1B
Gene Aliases
sTNF Receptor Type II, sTNFRII, TNFRSF1B, Tumor necrosis factor receptor 2, TNF-RII, TNF-R2, TNFR-II, TNFR75, TNFR80, p80 TNF-alpha receptor
Recombinant Human Tumor Necrosis Factor Receptor Superfamily Member 1B (TNFRSF1B)
Gene ID
7133
Accession Number
P20333
Organism
Human
Source
E. coli
Concentration
< 1.0 EU/μg of recombinant protein as determined by the LAL method.
Purity
>95% as determined by SDS-PAGE
Solubility
Reconstitute at 0.1mg/mL in sterile PBS.
Function
The ED(50) was determined by the dose-dependent proliferation of Immortalized human renal proximal tubule cells and was found to be <0.05ng/mL.
Molecular Weight
19
Shipping Conditions
Ambient Temperature
Storage Conditions
The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.
Appearance
Lyophilized Powder
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS.

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